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The way a copper peptide is formulated and delivered may affect how well it reaches the intended tissue
Tandon et al., 2022) the authors evaluated the quality of the clinical trial included in the qualitative synthesis, based on 5 items assessing the randomization process, blinding, and the dropout rate (i.e., the patients lost to follow-up)
The key point: the best option depends on the reason for low B12 and your clinical context
In two trials employing 1000 g/day oral vitamin B 12 , there was no clinically relevant difference in vitamin B 12 levels when compared with IM vitamin B 12
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